Prof. Dr. Stefan Gründer

Mail: sgruender@ukaachen.de
Room: 5th Floor, D4, Room 20

Tel: +49 241 80-88800
Fax: +49 241 80-82434

 

 

 

Curriculum vitae

 
1983 - 1989   Studies of Biology at the University of Cologne
1989 - 1990   Community service at the University of Cologne, Department of Otolaryngology, Head and Neck Surgery (Division of Audiology)
1990 - 1993   Doctoral work with Thomas J. Jentsch at the centre for Molecular Neurobiology Hamburg /ZMNH)
1993   PhD in Biology, University of Hamburg
1993 - 1997   Postdoctoral work with Bernard C. Rossier at the Institute of Pharmacology, Lausanne, Switzerland
1998 - 1999   Labhead at the Department of Otolaryngology, University of Tübingen; Group of J. Peter Ruppersberg
2000 - 2002   Head of a Research Group at the Medical School of the University of Tübingen
2003 - 2004   Research Group Leader at the Department of Physiology, University Tübingen
2004 - 2007   Associate Professor of Physiology, University Würzburg
2007   Acting Chairman of the Physiological Institute II, University Würzburg
since 2008   Full Professor of Physiology, RWTH-Aachen University
     

 

Honors and Awards
  • Teaching award Paula (awarded by the students of Aachen Medical School) for the Best Lecture 2011

 


Selected publications

  1. Chen X und Gründer S
    Permeating protons contribute to tachyphylaxis of Acid-Sensing Ion Channel (ASIC) 1a.
    J. Physiol (Lond.) , 579 (3), 657-670 (2007)

  2. Chen X, Polleichtner G, Kadurin I und Gründer S
    Zebrafish acid-sensing ion channel (ASIC) 4: characterization of homo- and heteromeric channels and identification of regions important for activation by H +.
    J. Biol. Chem ., 282, 30406-30413 (2007)

  3. Golubovic A, Kuhn A, Williamson M, Kalbacher H, Holstein TW, Grimmelikhuijzen CJ und Gründer S
    A peptide-gated ion channel form the freshwater polyp Hydra.
    J. Biol. Chem ., 282, 35098-35103 (2007)

  4. Paukert M, Chen X, Polleichtner G, Schindelin H und Gründer S
    Candidate amino acids involved in H +gating of acid-sensing ion channel (ASIC) 1a .
    J. Biol. Chem ., 283, 572-581 (2008)

  5. Kadurin I, Huber S und Gründer S (2009)
    A single conserved proline residue determines the membrane topology of stomatin.
    Biochem. J., 418: 587–594

  6. Springauf A, Gründer S (2010)
    An Acid-Sensing Ion Channel from Shark (Squalus Acanthias) Mediates Transient and Sustained Responses to Protons
    J. Physiol. 588 (5), 809-820

  7. Dürrnagel S, Kuhn A, Tsiairis CD, Williamson M, Kalbacher H, Grimmelikhuijzen CJ, Holstein TW and Gründer S
    Three homologous subunits form a high-affinity peptide-gated ion channel in Hydra.
    J. Biol. Chem., 285, 11958-11965 (2010)

  8. Wiemuth D und Gründer S
    A single amino acid tunes Ca2+ sensitivity of brain liver intestine Na+ channel (BLINaC).
    J. Biol. Chem., 285, 30404-30410 (2010)

  9. Springauf S, Bresenitz P und Gründer S
    The interaction between two extracellular linker regions controls sustained opening of acid-sensing ion channel 1.
    J. Biol. Chem., 286, 24374-24384 (2011) 

  10. Wiemuth D und Gründer S
    The pharmacological profile of brain liver intestine Na+ channel (BLINaC): inhibition by diarylamidines and activation by fenamates.
    Mol. Pharmacol., 80 (5), 911–919 (2011)

All publications PDF-File